Comparison of estradiol hemihydrate 10 µg vaginal tablets versus estradiol hemihydrate 10 µg vaginal gel in postmenopausal women with vaginal atrophy: a randomized crossover study
Noninferiority of the 10 µg estradiol hemihydrate tablet relative to the gel could not be established. However, both treatments exhibited clinical benefits and high patient satisfaction, providing valuable insights for therapeutic decision-making in postmenopausal vaginal atrophy.
Authors
- Prasong Tanmahasamut (ORCID: https://orcid.org/0000-0002-5152-1725)
- Chatchai Areeswate
- Thanyarat Wongwananuruk (ORCID: https://orcid.org/0000-0001-9380-7580)
- Panicha Chantrapanichkul (ORCID: https://orcid.org/0000-0002-7860-3181)
- Manee Rattanachaiyanont (ORCID: https://orcid.org/0000-0002-4533-9249)
- Kanchanok Taemamu
Institutions
- Siriraj Hospital (TH)
- Mahidol University (TH)
Publication Details
- Journal
- Archives of Gynecology and Obstetrics
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1007/s00404-025-08171-8
- Primary Topic
- Menopause: Health Impacts and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Mahidol University
- Faculty of Medicine Siriraj Hospital, Mahidol University