Nirsevimab is Effective Against Respiratory Syncytial Virus-Associated Hospitalization Among American Indian and Alaska Native Children in Their First and Second RSV Seasons in Alaska and the Southwest United States, 2023–2024
Nirsevimab is recommended to prevent severe respiratory syncytial virus (RSV)-associated illness among American Indian/Alaska Native (AI/AN) children <20 months of age. In a test-negative case-control analysis among 291 AI/AN children hospitalized during the 2023-2024 season, nirsevimab was 86.0% and 87.9% effective among children entering their first and second RSV seasons, respectively.
Authors
- Mila M. Prill (ORCID: https://orcid.org/0000-0002-1175-417X)
- Fernando Cardona (ORCID: https://orcid.org/0000-0001-7390-2265)
- Fatimah S. Dawood (ORCID: https://orcid.org/0000-0002-6609-376X)
- Judith Espinoza
- Rosalyn Singleton (ORCID: https://orcid.org/0000-0002-0317-3789)
- Rachel M. Hartman (ORCID: https://orcid.org/0000-0002-6837-4629)
- Natasha Halasa (ORCID: https://orcid.org/0000-0002-6381-1826)
- Nina Ritchie (ORCID: https://orcid.org/0000-0001-9885-4642)
- Christine Desnoyers
- Kelly Menachof
- Meredith McMorrow (ORCID: https://orcid.org/0000-0001-6363-4033)
- Chloe Hurley
- Catherine G. Sutcliffe (ORCID: https://orcid.org/0000-0001-8512-8326)
- Amanda Burrage (ORCID: https://orcid.org/0000-0002-8577-9433)
- James McAuley (ORCID: https://orcid.org/0009-0006-5590-5618)
- James W. Keck (ORCID: https://orcid.org/0000-0001-7193-065X)
- Rasmus Larsen (ORCID: https://orcid.org/0000-0001-8507-0523)
- James D. Chappell (ORCID: https://orcid.org/0000-0002-7382-7864)
- Angela P. Campbell (ORCID: https://orcid.org/0000-0002-2576-482X)
- Jennifer Dobson
- Marqia Sandoval
- L. Oxley
- Loretta Christensen
- Laura L. Hammitt
- Dennie Parker Riley
- Gilberto Alvarez-Colon
Institutions
- Centers for Disease Control and Prevention (US)
- Alaska Native Tribal Health Consortium (US)
- Johns Hopkins University (US)
- Indian Health Service (US)
- Yukon Kuskokwim Health Corporation (US)
- Tsehootsooi Medical Center (US)
- Gallup Indian Medical Center (US)
- Tuba City Regional Health Care (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1097/inf.0000000000004942
- Citations
- 1
- Primary Topic
- Respiratory viral infections research
- Type
- article
- Field-Weighted Citation Impact
- 1.35