Commensal skin bacteria interact with the innate immune system to promote tail regeneration in <i>Xenopus laevis</i> tadpoles
Taken together, our results suggest a previously undocumented role for Tlr2, possibly activated by peptidoglycan from Gram-positive commensal skin bacteria, in tipping the balance from wound repair to regenerative programmes in Xenopus laevis refractory stage tadpoles.
Authors
- Xochitl C. Morgan (ORCID: https://orcid.org/0000-0002-6264-6961)
- Daniel Hudson (ORCID: https://orcid.org/0000-0003-3120-3532)
- Robert C. Day (ORCID: https://orcid.org/0000-0002-0043-5149)
- Caroline W. Beck (ORCID: https://orcid.org/0000-0001-6489-7425)
- P. A. Chapman (ORCID: https://orcid.org/0000-0002-3303-9134)
- Joanna M. Ward
Institutions
- Harvard University (US)
- University of Otago (NZ)
Publication Details
- Journal
- Developmental Dynamics
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1002/dvdy.70088
- Primary Topic
- Antimicrobial Peptides and Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00