Oncolytic Properties of the Chimeric Poxvirus HOV-2 in Cholangiocarcinoma Models
In a human xenograft CCA tumor model, HOV-2 causes significant tumor regression with minimal toxicity. These results signify HOV-2 as a safe and effective treatment in a preclinical model of CCA.
Authors
- Anthony K. Park (ORCID: https://orcid.org/0000-0001-7692-8874)
- Annie Yang (ORCID: https://orcid.org/0000-0001-6997-6130)
- Yuman Fong (ORCID: https://orcid.org/0000-0002-8934-9959)
- Courtney Chen
- Zhifang Zhang (ORCID: https://orcid.org/0000-0002-1047-2402)
- Shyambabu Chaurasiya (ORCID: https://orcid.org/0000-0002-9543-5458)
- Yanghee Woo (ORCID: https://orcid.org/0000-0002-6676-0593)
- Sang‐In Kim (ORCID: https://orcid.org/0000-0003-3961-6083)
- Jennifer Cillis
- Yoya Vashi
Institutions
- Cedars-Sinai Medical Center (US)
- Johnson University (US)
- City of Hope (US)
Publication Details
- Journal
- Journal of the American College of Surgeons
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1097/xcs.0000000000001660
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00