Short-term association between ambient air pollution and heart rate variability: results from the population-based KORA S4 and FF4 studies
Short-term exposure to PM<sub>2.5</sub> and NO<sub>2</sub> impacts cardiac autonomic function, with varying effects across study waves due to aging, smoking, medication, and lower pollution levels. Even at low ambient concentrations, these exposures impaired autonomic function via inflammation and oxidative stress, underscoring the importance of stringent air quality standards and lifestyle interventions in reducing cardiovascular risk.
Authors
- Wayne E. Cascio (ORCID: https://orcid.org/0000-0003-1360-8093)
- Kathrin Wolf (ORCID: https://orcid.org/0000-0002-4343-201X)
- Stefan Kääb (ORCID: https://orcid.org/0000-0001-8824-3581)
- Yujiao Li
- Ina‐Maria Rückert‐Eheberg (ORCID: https://orcid.org/0000-0001-5418-283X)
- Alexandra Schneider
- Alexander Strom (ORCID: https://orcid.org/0000-0003-2402-2979)
- Georg Schmidt (ORCID: https://orcid.org/0000-0003-3692-5243)
- Susanne Breitner-Busch
- Siqi Zhang (ORCID: https://orcid.org/0000-0002-6239-8216)
- Annette Peters
Institutions
- Environmental Protection Agency (US)
- Zimmer Biomet (Netherlands) (NL)
- Helmholtz Zentrum München (DE)
- Polyclinic Medical University (CH)
- German Centre for Cardiovascular Research (DE)
- Deutsches Diabetes-Zentrum e.V. (DE)
- German Center for Diabetes Research (DE)
- Heinrich Heine University Düsseldorf (DE)
- Technical University of Munich (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Particle and Fibre Toxicology
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1186/s12989-025-00645-6
- Citations
- 1
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 1.20
Funders
- Bundesministerium für Bildung und Forschung
- China Scholarship Council
- Helmholtz Zentrum München
- Münchner Zentrum für Gesundheitswissenschaften