Prevalence characteristics of human papillomavirus among women in Henan Province of China

This study provides baseline data on the epidemiological characteristics of HPV. The prevalence of HPV among women in Henan Province is high. The highest prevalence is among women less than 20 years. The predominant genotypes identified were HPV 52, 58, 16, and 53. This genotype distribution suggests that the Gardasil 9 vaccine, which covers HPV 52, 58, and 16, could potentially address a significant proportion of high-risk HPV infections in this population. The high prevalence of HPV 53, a genotype not targeted by current vaccines, warrants further investigation into its oncogenic role and epidemiological significance.

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Publication Details

Journal
Virology Journal
Published
2025-10-17
DOI
https://doi.org/10.1186/s12985-025-02953-x
Primary Topic
Cervical Cancer and HPV Research
Type
article
Field-Weighted Citation Impact
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article

Prevalence characteristics of human papillomavirus among women in Henan Province of China

C. G. Zhuang, Xiaoying Zhu, S Li
Virology Journal
Cervical Cancer and HPV Research
article

Prevalence characteristics of human papillomavirus among women in Henan Province of China

C. G. Zhuang, Xiaoying Zhu, S Li
article en

Abstract

This study provides baseline data on the epidemiological characteristics of HPV. The prevalence of HPV among women in Henan Province is high. The highest prevalence is among women less than 20 years. The predominant genotypes identified were HPV 52, 58, 16, and 53. This genotype distribution suggests that the Gardasil 9 vaccine, which covers HPV 52, 58, and 16, could potentially address a significant proportion of high-risk HPV infections in this population. The high prevalence of HPV 53, a genotype not targeted by current vaccines, warrants further investigation into its oncogenic role and epidemiological significance.

Virology JournalVol. 22(1)
Henan Provincial People's Hospital (CN), Zhengzhou People's Hospital (CN), First Affiliated Hospital of Zhengzhou University (CN)
Openalex Percentile: Top 60%
Cervical Cancer and HPV Research
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Prevalence characteristics of human papillomavirus among women in Henan Province of China — C. G. Zhuang, Xiaoying Zhu, et al. · Virology Journal (2025) | TGRS Research Map | TGRS