Activity-dependent modulation of glutamate, glutamine and glutathione in first-episode schizophrenia: A 7T functional MRS study
A potential inability to mount an appropriate antioxidant response to short-term oxidative stress may occur in the early stages of schizophrenia. A longitudinal study of fMRS is required to better understand the regulation of oxidative stress across the different stages of schizophrenia.
Authors
- Sabrina D. Ford (ORCID: https://orcid.org/0000-0003-3911-741X)
- Michael Mackinley (ORCID: https://orcid.org/0000-0002-9693-7353)
- Peter Jeon (ORCID: https://orcid.org/0000-0002-0828-4461)
- Kara Dempster (ORCID: https://orcid.org/0000-0002-5903-5051)
- Jean Théberge (ORCID: https://orcid.org/0000-0001-7578-4469)
- Lena K. Palaniyappan (ORCID: https://orcid.org/0000-0003-1640-7182)
Institutions
- Western University (CA)
- Dalhousie University (CA)
- Lawson Health Research Institute (CA)
- Douglas Mental Health University Institute (CA)
Publication Details
- Journal
- Schizophrenia Research
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1016/j.schres.2025.10.008
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00