Pharmacokinetics and Pharmacodynamics of a Novel Formulation of Furosemide Administered as a Single Subcutaneous Injection
Furosemide 80 mg/mL SC injection was generally well tolerated and had bioavailability, diuresis, natriuresis, and kaliuresis consistent with those of furosemide IV.
Authors
- Michele Dibattista (ORCID: https://orcid.org/0000-0002-3955-4663)
- Fatima Saba
- Taylor Williams
- Barbara Cornelius
- Harry Alcorn
- James E. Udelson (ORCID: https://orcid.org/0000-0003-2998-910X)
- John Mohr (ORCID: https://orcid.org/0000-0002-0746-4110)
- Phanisyam Kamineni
Institutions
- Tufts University (US)
- Tufts Medical Center (US)
- scPharmaceuticals (United States) (US)
- AdventHealth Tampa (US)
- Cardiovascular Clinical Science Foundation (US)
- Alcorn State University (US)
Publication Details
- Journal
- Clinical Therapeutics
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1016/j.clinthera.2025.09.004
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00