APOE4 carriership status influences [11C]PiB white matter retention in cognitively healthy older adults
A decrease in NAWM [<sup>11</sup>C]PiB retention is suggestive of myelin damage prior to the onset of cognitive decline in APOE4 homozygotes.
Authors
- Semi Helin (ORCID: https://orcid.org/0000-0002-9405-7301)
- Riitta Parkkola (ORCID: https://orcid.org/0000-0001-8046-315X)
- Anniina Snellman
- Marco Bucci (ORCID: https://orcid.org/0000-0002-5206-8651)
- Jouni Tuisku (ORCID: https://orcid.org/0000-0003-0965-9365)
- Laura L. Ekblad (ORCID: https://orcid.org/0000-0002-5863-8088)
- Claudia Tato-Fernández (ORCID: https://orcid.org/0009-0008-8448-8678)
- Juha O. Rinne
Institutions
- University of Turku (FI)
- Turku University Hospital (FI)
- Turku PET Centre (FI)
Publication Details
- Journal
- Neurobiology of Disease
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1016/j.nbd.2025.107140
- Primary Topic
- Power Line Communications and Noise
- Type
- article
- Field-Weighted Citation Impact
- 0.00