The influence of VEGFR-2 blockade and focused ultrasound blood–brain barrier opening on the glioma-immune landscape
DC101-mediated vascular normalization beneficially remodels the GBM TME and creates a quiescent platform for supporting future FUS-based therapeutic delivery. This combinatorial strategy offers a promising approach to overcoming BBB-related barriers in glioma treatment.
Authors
- Tajie H. Harris (ORCID: https://orcid.org/0000-0002-1355-2109)
- Joshua D. Samuels (ORCID: https://orcid.org/0000-0001-5662-3758)
- Anna Debski (ORCID: https://orcid.org/0000-0001-7288-0842)
- Matthew R. DeWitt
- Matthew R. Hoch
- Katherine M. Nowak (ORCID: https://orcid.org/0000-0003-3860-5366)
- Catherine M. Gorick (ORCID: https://orcid.org/0000-0002-0139-3438)
- Richard J. Price (ORCID: https://orcid.org/0000-0002-0237-2102)
- Victoria R. Breza (ORCID: https://orcid.org/0000-0003-2294-7222)
- Benjamin Purow (ORCID: https://orcid.org/0000-0001-7372-6062)
- Timothy N. J. Bullock (ORCID: https://orcid.org/0000-0001-6141-3261)
- Ji Song
Institutions
- University of Virginia Medical Center (US)
- University of Virginia (US)
Publication Details
- Journal
- Neuro-Oncology Advances
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1093/noajnl/vdaf221
- Primary Topic
- Ultrasound and Hyperthermia Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00