Interaction between the level of human papillomavirus integration and human papillomavirus type on the risk of grade 3 cervical intraepithelial neoplasia or more severe in human papillomavirus integration positive women: A cross‐sectional study
There was an interaction between HPV type and NHIR on CIN3+. HPV integration can further assess a patient's risk based on HPV genotyping detection, which is conducive to reducing missed diagnoses. The NHIR might be a potential biomarker for early warning and precise identification of high-risk CIN lesions.
Authors
- Ting Hu (ORCID: https://orcid.org/0000-0002-0538-0300)
- Xin Liu (ORCID: https://orcid.org/0000-0003-3585-8720)
- Xi Li (ORCID: https://orcid.org/0000-0001-9185-7728)
- Zhijie Wang (ORCID: https://orcid.org/0000-0003-4619-0543)
- Xiaoyuan Huang
- Liang He (ORCID: https://orcid.org/0000-0001-6711-2021)
- Qiongying Lyu (ORCID: https://orcid.org/0009-0002-9496-8380)
- Hu Zhou (ORCID: https://orcid.org/0000-0001-6295-8212)
- Yixuan Cai
- Shimin Chen (ORCID: https://orcid.org/0000-0001-5289-1309)
Institutions
- Wuhan University of Technology (CN)
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- International Journal of Gynecology & Obstetrics
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1002/ijgo.70584
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00