Inadequate Status of Multiple B Vitamins is Common Among Women in Oromia Region, Ethiopia

The true burden of micronutrient deficiencies among women of reproductive age (WRA) in many resource-limited settings is likely underestimated, as data on several "neglected micronutrients" remain sparse. We used data from a cross-sectional survey of 100 nonpregnant WRA in the region of Oromia, Ethiopia to describe the prevalence of various micronutrient deficiencies and other indicators of nutritional status. The prevalences of anemia (hemoglobin < 13.4 g/dL, adjusted for altitude) and iron deficiency (inflammation-adjusted serum ferritin < 15 ug/L) were 7.1% and 4.0%, respectively. However, 100.0% of females were deficient in riboflavin [erythrocyte glutathione reductase activation coefficient (EGRac) > 1.4], and the prevalences of thiamine insufficiency [erythrocyte transketolase activity coefficient (ETKac) 1.15-1.25], folate insufficiency [red blood cell (RBC) folate < 748 nmol/L], and vitamin B12 insufficiency (serum B12 < 221 pmol/L) were 38.8%, 96.0%, and 52.6%, respectively. Future surveys should include a more comprehensive assessment of B vitamins to corroborate these findings and inform the design of appropriate interventions to improve status.

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Publication Details

Journal
Current Developments in Nutrition
Published
2025-10-17
DOI
https://doi.org/10.1016/j.cdnut.2025.107578
Primary Topic
Folate and B Vitamins Research
Type
article
Field-Weighted Citation Impact
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article

Inadequate Status of Multiple B Vitamins is Common Among Women in Oromia Region, Ethiopia

Mengistu Fereja, Homero Martı́nez, Christine M. McDonald, Kerry S. Jones et al.
Current Developments in Nutrition
Folate and B Vitamins Research
article

Inadequate Status of Multiple B Vitamins is Common Among Women in Oromia Region, Ethiopia

Mengistu Fereja, Homero Martı́nez, Christine M. McDonald, Kerry S. Jones, Mandana Arabi, Charles D. Arnold, Meseret Woldeyohannes, Isaac Agbemafle, Kenneth H. Brown, Masresha Tessema, Biniyam Tesfaye
article en

Abstract

The true burden of micronutrient deficiencies among women of reproductive age (WRA) in many resource-limited settings is likely underestimated, as data on several "neglected micronutrients" remain sparse. We used data from a cross-sectional survey of 100 nonpregnant WRA in the region of Oromia, Ethiopia to describe the prevalence of various micronutrient deficiencies and other indicators of nutritional status. The prevalences of anemia (hemoglobin < 13.4 g/dL, adjusted for altitude) and iron deficiency (inflammation-adjusted serum ferritin < 15 ug/L) were 7.1% and 4.0%, respectively. However, 100.0% of females were deficient in riboflavin [erythrocyte glutathione reductase activation coefficient (EGRac) > 1.4], and the prevalences of thiamine insufficiency [erythrocyte transketolase activity coefficient (ETKac) 1.15-1.25], folate insufficiency [red blood cell (RBC) folate < 748 nmol/L], and vitamin B12 insufficiency (serum B12 < 221 pmol/L) were 38.8%, 96.0%, and 52.6%, respectively. Future surveys should include a more comprehensive assessment of B vitamins to corroborate these findings and inform the design of appropriate interventions to improve status.

Current Developments in NutritionVol. 9(11)
International Development Research Centre (CA), University of Rhode Island (US), University of California, San Francisco (US), University of Cambridge (GB), University of Health and Allied Sciences (GH), Ethiopian Public Health Institute (ET), MRC Epidemiology Unit (GB), Nutrition International (CA), University of California, Davis (US)
Openalex Percentile: Top 57%
Folate and B Vitamins Research
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