Holmes tremor following midbrain hemorrhage – An illustrative case

This case highlights a rare manifestation of HT secondary to mesencephalic hemorrhage complicated by obstructive hydrocephalus. The delayed onset and resistance to pharmacologic therapy emphasize the diagnostic and therapeutic complexity of HT. Clinicians should be vigilant in recognizing this condition in similar clinical scenarios and consider a tailored strategy, including delayed consideration of functional neurosurgery once hydrocephalus has stabilized.

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Publication Details

Journal
Surgical Neurology International
Published
2025-10-17
DOI
https://doi.org/10.25259/sni_668_2025
Primary Topic
Neurological disorders and treatments
Type
article
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article

Holmes tremor following midbrain hemorrhage – An illustrative case

Giovanni Cirillo, Angela Lupo, Domenico Cassitto, Antonio Fasano et al.
Surgical Neurology International
Neurological disorders and treatments
article

Holmes tremor following midbrain hemorrhage – An illustrative case

Giovanni Cirillo, Angela Lupo, Domenico Cassitto, Antonio Fasano, A. Giaquinta, Cosimo Damiano Gianfreda, Marta Lorenzo, Alessandro Melatini, Matteo Esposito, Haleema Sadia, Sohaib Ali, Marilena Rolli, Francesco Mastromatteo, Dario Palescandolo
article en

Abstract

This case highlights a rare manifestation of HT secondary to mesencephalic hemorrhage complicated by obstructive hydrocephalus. The delayed onset and resistance to pharmacologic therapy emphasize the diagnostic and therapeutic complexity of HT. Clinicians should be vigilant in recognizing this condition in similar clinical scenarios and consider a tailored strategy, including delayed consideration of functional neurosurgery once hydrocephalus has stabilized.

Surgical Neurology InternationalVol. 16
University of Campania "Luigi Vanvitelli" (IT), Ospedale Vito Fazzi (IT)
Openalex Percentile: Top 58%
Neurological disorders and treatments
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Holmes tremor following midbrain hemorrhage – An illustrative case — Giovanni Cirillo, Angela Lupo, et al. · Surgical Neurology International (2025) | TGRS Research Map | TGRS