TVB C++: A Fast and Flexible Back‐End for The Virtual Brain

This study introduces TVB C++, a streamlined and fast C++ Back-End for The Virtual Brain (TVB), a renowned platform and a benchmark tool for full-brain simulation. TVB C++ is engineered with speed as a primary focus while retaining the flexibility and ease of use characteristic of the original TVB platform. Positioned as a complementary tool, TVB serves as a prototyping platform, whereas TVB C++ becomes indispensable when performance is paramount, particularly for large-scale simulations and leveraging advanced computation facilities like supercomputers. Developed as a TVB-compatible Back-End, TVB C++ seamlessly integrates with the original TVB implementation, facilitating effortless usage. Users can easily configure TVB C++ to execute the same code as in TVB but with enhanced performance and parallelism capabilities. As a consequence, TVB C++ will enable the widespread use of individualized models that will open the possibility of designed tailored solutions at the individual patient level.

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Publication Details

Journal
Advanced Science
Published
2025-10-17
DOI
https://doi.org/10.1002/advs.202406440
Citations
1
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
1.43

Funders

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article en
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Abstract

This study introduces TVB C++, a streamlined and fast C++ Back-End for The Virtual Brain (TVB), a renowned platform and a benchmark tool for full-brain simulation. TVB C++ is engineered with speed as a primary focus while retaining the flexibility and ease of use characteristic of the original TVB platform. Positioned as a complementary tool, TVB serves as a prototyping platform, whereas TVB C++ becomes indispensable when performance is paramount, particularly for large-scale simulations and leveraging advanced computation facilities like supercomputers. Developed as a TVB-compatible Back-End, TVB C++ seamlessly integrates with the original TVB implementation, facilitating effortless usage. Users can easily configure TVB C++ to execute the same code as in TVB but with enhanced performance and parallelism capabilities. As a consequence, TVB C++ will enable the widespread use of individualized models that will open the possibility of designed tailored solutions at the individual patient level.

Advanced ScienceVol. 13(2)
Institució Catalana de Recerca i Estudis Avançats (ES), Central European Institute of Technology (CZ), Universitat Pompeu Fabra (ES), Czech Academy of Sciences (CZ), Universitat de Girona (ES), Institut de Neurosciences des Systèmes (FR), Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
European Commission, Deutsche Forschungsgemeinschaft, Agence Nationale de la Recherche, Berlin Institute of Health, Berlin University Alliance, HORIZON EUROPE Framework Programme, Agència de Gestió d'Ajuts Universitaris i de Recerca, European Regional Development Fund, Agencia Estatal de Investigación
Openalex Percentile: Top 15%
Functional Brain Connectivity Studies
1.43
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