Using natural language processing to extract information from clinical text in electronic medical records for populating clinical registries: a systematic review

To date, the application of NLP methods to clinical text for populating clinical registries has been limited in both the number of published studies and the scope of implementation. The NLP methods used thus far face significant challenges in effectively managing the complexity and diversity of clinical text and data elements. Moreover, the performance of the NLP methods varied significantly. This review underscores the need for a robust and adaptable NLP framework. Generative LLMs may provide direction for future research, but their use must account for challenges such as accuracy, cost, privacy, and limited supporting evidence.

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Publication Details

Journal
Journal of the American Medical Informatics Association
Published
2025-09-25
DOI
https://doi.org/10.1093/jamia/ocaf176
Citations
4
Primary Topic
Machine Learning in Healthcare
Type
article
Field-Weighted Citation Impact
9.92
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article

Using natural language processing to extract information from clinical text in electronic medical records for populating clinical registries: a systematic review

Tim Churches, Blanca Gallego Luxan, Sze‐Yuan Ooi, Georgina Kennedy et al.
4 citations
Journal of the American Medical Informatics Association
Machine Learning in Healthcare
9.92
article

Using natural language processing to extract information from clinical text in electronic medical records for populating clinical registries: a systematic review

Tim Churches, Blanca Gallego Luxan, Sze‐Yuan Ooi, Georgina Kennedy, Geoff P. Delaney, Victoria Blake, Louisa Jorm, Leibo Liu, Matthew Barman
article en
4 citations

Abstract

To date, the application of NLP methods to clinical text for populating clinical registries has been limited in both the number of published studies and the scope of implementation. The NLP methods used thus far face significant challenges in effectively managing the complexity and diversity of clinical text and data elements. Moreover, the performance of the NLP methods varied significantly. This review underscores the need for a robust and adaptable NLP framework. Generative LLMs may provide direction for future research, but their use must account for challenges such as accuracy, cost, privacy, and limited supporting evidence.

Journal of the American Medical Informatics AssociationVol. 33(2)
UNSW Sydney (AU), Prince of Wales Hospital (AU), Ingham Institute (AU), South Western Sydney Local Health District (AU), Western Sydney University (AU)
Openalex Percentile: Top 2%
Machine Learning in Healthcare
9.92
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