Unlocking the Antiviral Potential of Chalcones: A Computational Approach against Dengue Virus NS5 Protein

BL-3 shows strong potential as an NS5 methyltransferase inhibitor due to its optimal binding, safety profile, and electronic properties. It is recommended for further lead optimization and experimental validation as a candidate anti-DENV agent.

Authors

Institutions

Publication Details

Journal
Journal of Vector Borne Diseases
Published
2025-10-16
DOI
https://doi.org/10.4103/jvbd.jvbd_187_25
Primary Topic
Mosquito-borne diseases and control
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Unlocking the Antiviral Potential of Chalcones: A Computational Approach against Dengue Virus NS5 Protein

Louis Odinakaose Ezediuno, B. D. J. George, Bill Akponanabofa Ekolama
Journal of Vector Borne Diseases
Mosquito-borne diseases and control
article

Unlocking the Antiviral Potential of Chalcones: A Computational Approach against Dengue Virus NS5 Protein

Louis Odinakaose Ezediuno, B. D. J. George, Bill Akponanabofa Ekolama
article en

Abstract

BL-3 shows strong potential as an NS5 methyltransferase inhibitor due to its optimal binding, safety profile, and electronic properties. It is recommended for further lead optimization and experimental validation as a candidate anti-DENV agent.

Journal of Vector Borne Diseases
Obong University (NG)
Openalex Percentile: Top 61%
Mosquito-borne diseases and control
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Unlocking the Antiviral Potential of Chalcones: A Computational Approach against Dengue Virus NS5 Protein — Louis Odinakaose Ezediuno, B. D. J. George, et al. · Journal of Vector Borne Diseases (2025) | TGRS Research Map | TGRS