Choroidal thickness as a biomarker of systemic inflammation in patients with polymyalgia rheumatica
We found that CT was high in patients with recent diagnosis of PMR and decreases significantly after 3 and 6 months of corticosteroid therapy. There is a 95% of concordance between CT and CRP as well as between CT and PMR activity scores. Our findings suggest that CT is useful as a noninvasive, imaging-based biomarker of systemic inflammation in patients with PMR. More studies are needed to confirm these preliminary results.
Authors
- M. D. M. Esteban-Ortega
- Ana Esteban (ORCID: https://orcid.org/0000-0002-7693-0656)
- Maji Jose (ORCID: https://orcid.org/0000-0003-2504-4440)
- Martina Steiner (ORCID: https://orcid.org/0000-0003-1617-4454)
- Israel J. Thuissard (ORCID: https://orcid.org/0000-0002-6990-0619)
- GUILLERMO MARQUEZ NAJERA
- Tarek Harb (ORCID: https://orcid.org/0000-0002-2573-5260)
- Jorge Juan González Martín (ORCID: https://orcid.org/0000-0002-3169-0206)
- Tatiana Cobo‐Ibáñez (ORCID: https://orcid.org/0000-0002-9220-1867)
- Santiago Muñoz‐Fernández (ORCID: https://orcid.org/0000-0002-2758-2085)
- Patricia Richi (ORCID: https://orcid.org/0000-0003-2277-6814)
- Andrés Acosta (ORCID: https://orcid.org/0000-0003-2286-489X)
- Marcelo Paredes (ORCID: https://orcid.org/0000-0001-8124-6202)
- C Vergara-Dangond (ORCID: https://orcid.org/0009-0000-4952-6992)
- Laura Trives-Folguera (ORCID: https://orcid.org/0000-0002-7258-8136)
- Patricia Bogas Schay
- Karla Camila Rivero Gómez
- Liz Romero-Bogado (ORCID: https://orcid.org/0000-0002-1313-5225)
- Isabel de la Cámara-Fernández
- Raquel Coca-Serrano
Institutions
- Hospital Universitario HM Sanchinarro (ES)
- Hospital Universitario Infanta Sofía (ES)
- Universidad de Huelva (ES)
- Universidad Europea de Madrid (ES)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-10-17
- DOI
- https://doi.org/10.3389/fmed.2025.1689327
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Comunidad de Madrid