Correlation of immune cell subsets in the tumor microenvironment and peripheral blood with immunotherapy response in esophageal squamous cell carcinoma

TIM3<sup>+</sup> CD8<sup>+</sup> T cells are a promising predictive biomarker for immunotherapy outcomes in ESCC. These findings highlight their potential to guide personalized treatment strategies in clinical practice.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-10-17
DOI
https://doi.org/10.3389/fimmu.2025.1633748
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
0.00
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article

Correlation of immune cell subsets in the tumor microenvironment and peripheral blood with immunotherapy response in esophageal squamous cell carcinoma

Wei Chen, Min Tao, Lian Gong, Mengyao Wu et al.
Frontiers in Immunology
Immune Cell Function and Interaction
article

Correlation of immune cell subsets in the tumor microenvironment and peripheral blood with immunotherapy response in esophageal squamous cell carcinoma

Wei Chen, Min Tao, Lian Gong, Mengyao Wu, Yahu Li
article en

Abstract

TIM3<sup>+</sup> CD8<sup>+</sup> T cells are a promising predictive biomarker for immunotherapy outcomes in ESCC. These findings highlight their potential to guide personalized treatment strategies in clinical practice.

Frontiers in ImmunologyVol. 16
Soochow University (CN), Longgang Central Hospital (CN), Nantong Tumor Hospital (CN), Taixing People's Hospital (CN), Second Affiliated Hospital of Soochow University (CN), First Affiliated Hospital of Soochow University (CN), Shenzhen Third People’s Hospital (CN)
Openalex Percentile: Top 69%
Immune Cell Function and Interaction
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Correlation of immune cell subsets in the tumor microenvironment and peripheral blood with immunotherapy response in esophageal squamous cell carcinoma — Wei Chen, Min Tao, et al. · Frontiers in Immunology (2025) | TGRS Research Map | TGRS