Insights Into CEST Contrast at 2 ppm in Enhancing and Nonenhancing Lesions From Glioma Patients Scanned at 7 T
CEST 2 ppm pool contrast was distinctive between normal-appearing white matter, enhancing and nonenhancing tumor lesions, independently of the metric used. These findings suggest that the CEST pool at 2 ppm provides a valuable noninvasive contrast for imaging gliomas.
Authors
- Johan A F Koekkoek (ORCID: https://orcid.org/0000-0002-3648-9616)
- Linda Dirven (ORCID: https://orcid.org/0000-0001-9157-9895)
- Jeroen de Bresser (ORCID: https://orcid.org/0000-0003-0759-8407)
- Ece Ercan (ORCID: https://orcid.org/0000-0002-8187-2075)
- Matthias J.P. van Osch (ORCID: https://orcid.org/0000-0001-7034-8959)
- Bárbara Schmitz‐Abecassis (ORCID: https://orcid.org/0000-0003-1776-4560)
- Martin Klein
Institutions
- Leiden University Medical Center (NL)
- Medisch Centrum Haaglanden (NL)
- Philips (Netherlands) (NL)
- Delta State University (US)
Publication Details
- Journal
- NMR in Biomedicine
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1002/nbm.70161
- Primary Topic
- Lanthanide and Transition Metal Complexes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Medical Delta