Reducing contrast media dosage for pulmonary embolism CTPA in PCD-CT: a comparative study of EID-CT and PCD-CT in the era of individualized protocolling
Question The feasibility of CM reduction in PCD-CT vs EID-CT with highly individualized CM protocols, while maintaining diagnostic IQ. Findings PCD-CT reduces total iodine load by 26.7% and CT dose index volume by 24.4% compared to EID-CT, with comparable objective and subjective diagnostic IQ. Clinical relevance This approach enables CM reduction, potentially lowering patient risk and providing environmental and financial benefits. Additionally, PCD-CT allows for CM and radiation dose reduction while maintaining comparable IQ.
Authors
- Cécile R. L. P. N. Jeukens (ORCID: https://orcid.org/0000-0003-1403-8301)
- Hester A. Gietema (ORCID: https://orcid.org/0000-0001-6077-1446)
- Bibi Martens (ORCID: https://orcid.org/0000-0003-3105-6640)
- Joachim Ernst Wildberger (ORCID: https://orcid.org/0000-0002-4810-6854)
- Thomas G. Flohr (ORCID: https://orcid.org/0000-0002-9524-5531)
- Eva J I Hoeijmakers (ORCID: https://orcid.org/0009-0007-7026-3112)
- Lion Stammen (ORCID: https://orcid.org/0009-0005-8031-8223)
- Janneke Vandewall
Institutions
- Maastricht University Medical Centre (NL)
- Maastricht University (NL)
- Siemens Healthineers (Germany) (DE)
Publication Details
- Journal
- European Radiology
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1007/s00330-025-12054-6
- Citations
- 1
- Primary Topic
- Advanced X-ray and CT Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.67