<i>Fusarium solani</i> Activates PANoptosis and Modulates Immune Response in Fungal Keratitis
F. solani infection and DON exposure induce PANoptosis in fungal keratitis, leading to significant inflammatory responses. These results suggest that targeting PANoptosis signaling pathways may represent a novel therapeutic approach for treating fungal keratitis.
Authors
- Xingbo Teng
- Xuewei Xiong (ORCID: https://orcid.org/0009-0005-7310-434X)
- Guocheng Yu
- Xiaoyi Fan
- Xiao-Yuan Sha
- Chang‐Lin Wu (ORCID: https://orcid.org/0000-0002-5826-192X)
- Lian Liu (ORCID: https://orcid.org/0000-0001-6489-227X)
- Jingxiang Zhong (ORCID: https://orcid.org/0000-0003-3204-5329)
Institutions
- Wuhan University (CN)
- Weifang People's Hospital (CN)
- Renmin Hospital of Wuhan University (CN)
- First Affiliated Hospital of Jinan University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1167/iovs.66.13.27
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00