Survival rate can be associated with body weight in clinical cases of canine parvovirus: A critical appraisal of the evidence

This critically appraised topic (CAT) explored the association between body weight and survival in dogs with canine parvovirus (CPV). A systematic literature search identified six peer-reviewed studies published between 1978 and 2024 that met predefined inclusion criteria. Four of the six studies demonstrated a significant association between lower body weight and increased mortality. While some studies undertook multivariable analysis to account for confounders, limitations including inconsistencies in study design, retrospective data collection, and limited control for variables such as age, breed, and body condition score (BCS) reduce the overall strength of the conclusions. Overall, there is moderate evidence to suggest that lower body weight may be a negative prognostic factor in CPV survival. Further prospective research with standardised methodology is essential to validate these findings and disentangle the impact of confounders such as age, breed, and BCS.