Clinical features of yellow fever in cases from Bolivia, Ecuador, Colombia, and Peru (2023–2025): A descriptive retrospective study
This study provides one of the first systematic clinical characterizations of YF cases from Bolivia, Ecuador, Colombia, and Peru. The high fatality rate, despite the young age of patients, underscores the vulnerability of populations in resource-limited, peri-Amazonian settings. Severe hepatic dysfunction, hemorrhage, and systemic collapse were consistent hallmarks of the disease. These findings highlight the urgent need to strengthen vaccination coverage, enhance clinical recognition, and expand access to critical care in outbreak-prone areas of South America.
Authors
- Miguel Villegas-Chiroque (ORCID: https://orcid.org/0000-0002-8090-8224)
- Lysien I. Zambrano (ORCID: https://orcid.org/0000-0001-9002-5807)
- Juan Pablo Escalera-Antezana (ORCID: https://orcid.org/0000-0003-1235-0019)
- Jorge Luis Aviles-Sarmiento
- Sergio Luis Aguilar-Martinez
- Alfonso Javier Rodriguez-Morales (ORCID: https://orcid.org/0000-0001-9773-2192)
- Rachel S. Gross (ORCID: https://orcid.org/0000-0003-4613-6985)
- D. Katterine Bonilla‐Aldana (ORCID: https://orcid.org/0000-0002-9412-2556)
- Wilmer E. Villamil‐Gómez (ORCID: https://orcid.org/0000-0002-5492-3455)
- Jorge Luis Bonilla-Aldana (ORCID: https://orcid.org/0000-0003-3127-5798)
- Nelson Delgado-Torres (ORCID: https://orcid.org/0000-0003-3832-0395)
- Claudia Marcela Montenegro-Narváez
- Nestor Freddy Armijo-Subieta
- Carlos Eduardo Gonzales-Flores (ORCID: https://orcid.org/0000-0002-7190-3536)
- Johana E. Aparicio-Sigueñas (ORCID: https://orcid.org/0009-0001-1595-649X)
- Cristian Pacheco-Jimenez
- Rodrigo Daniel Montesinos-Jove
- Claudia Nathaly Arauco-Gutierrez
- Ivan Camilo Sanchez-Rojas
- Catherin Lorena Solarte-Jimenez
- Eibar Camilo Chamorro-Velazco
- Glinys Edith Diaz-Llerena
- Cristian Daniel Arevalo
- Olga Lucia Cuasquer-Posos
- Hugo Antonio Castro-Calderón
- Boris Chang-Cheng
- Juan Esteban Callejas-Patiño
- James Mosquera-Suárez
- Oscar Eduardo Llanque-Espinoza
- Jesus Villamil-Macareno
- Gabriela Belén Pineda-Bersoza
Institutions
- Universidad Mayor de San Andrés (BO)
- National Autonomous University of Honduras (HN)
- Universidad El Bosque (CO)
- National University of San Marcos (PE)
- Universidad Autónoma de Bucaramanga (CO)
- Korea University (KR)
- Universidad Científica del Sur (PE)
- Universidad Mayor de San Simón (BO)
- Research Institute Orion (UA)
- Universidad Metropolitana (CO)
- Departamento de Epidemiología (GT)
- Hospital Quirónsalud Sagrado Corazón (ES)
- Centro de Información y Desarrollo de la Mujer (BO)
- Universidad Nacional de Loja (EC)
- Universidad Católica Bolivia San Pablo (BO)
- Ministerio de Salud (BO)
- Universidad Privada Boliviana (BO)
- Universidad Simón Bolívar (CO)
- Institución Universitaria Colegios de Colombia (CO)
- Departamento de Salud (ES)
- Hospital Universitario San Ignacio (CO)
- Universidad de Lambayeque (PE)
- Institución Universitaria Visión de las Américas (CO)
- Universidad Privada Abierta Latinoamericana (BO)
- Arcadis (Czechia) (CZ)
- UCLouvain (BE)
Publication Details
- Journal
- New Microbes and New Infections
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1016/j.nmni.2025.101651
- Citations
- 5
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 9.39