Loneliness, Genetic Susceptibility, Brain Structure, and the Risk of Schizophrenia: A Large Prospective Study
Loneliness independently predicts increased SZ risk and is associated with widespread brain volume changes, especially in genetically vulnerable individuals. Addressing loneliness may be a key strategy to mitigate SZ development and brain structural alterations.
Authors
- Zhongpeng Dai (ORCID: https://orcid.org/0000-0001-9645-5824)
- Jianing Wang (ORCID: https://orcid.org/0009-0002-5203-8767)
Institutions
- Monash University (AU)
- University of Hong Kong (HK)
Publication Details
- Journal
- Schizophrenia Bulletin
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1093/schbul/sbaf179
- Citations
- 1
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.43