A Double‐Layer <sup>1</sup> H/ <sup>23</sup> Na Transceiver Array for Human Brain MRI at 7T
With the increasing adoption of ultra-high-field (UHF) systems, sodium (<sup>23</sup>Na) imaging is undergoing clinical translation. However, existing commercially available dual-tuned coils, while demonstrating adequate sodium signal-to-noise ratio (SNR), fail to meet the requirements for high-resolution proton (<sup>1</sup>H) structural imaging, resulting in suboptimal workflow efficiency during integrated multi-nucleus examinations. In this work, we present a novel double-layer <sup>1</sup>H/<sup>23</sup>Na transceiver array with eight channels per nucleus for human brain MRI at 7T. The proposed array achieved 64% of the <sup>1</sup>H SNR of the 32-channel receive array commonly used in clinical practice. By integrating dual-nucleus imaging capabilities within a single platform, this design eliminates coil-switching requirements and post-acquisition registration, thereby streamlining clinical workflows and advancing sodium MRI translational feasibility.
Authors
- Jianxun Qu (ORCID: https://orcid.org/0000-0003-4587-6439)
- Chuanlong Guo (ORCID: https://orcid.org/0000-0001-7901-156X)
- Zhiyan Quan
- Feiyang Lou (ORCID: https://orcid.org/0009-0000-2113-7119)
- Armin Michael Nagel (ORCID: https://orcid.org/0000-0003-0948-1421)
- Caohui Duan (ORCID: https://orcid.org/0009-0003-0517-8692)
- Xiaotong Zhang (ORCID: https://orcid.org/0000-0002-9197-1421)
- Xin Lou (ORCID: https://orcid.org/0000-0001-7196-9861)
Institutions
- German Cancer Research Center (DE)
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Heidelberg University (DE)
- Chinese PLA General Hospital (CN)
- Universitätsklinikum Erlangen (DE)
- Zhejiang Institute of Mechanical and Electrical Engineering (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Siemens (China) (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- NMR in Biomedicine
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1002/nbm.70162
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00