Bioinformatic Identification of CRISPR–Cas Systems in Leptospira Genus: An Update on Their Distribution Across 77 Species
The presence of Cas proteins, direct repeats, and spacer sequences with homology to bacteriophage genomes provides evidence for a functional CRISPR-Cas system in at least 19 species.
Authors
- Marco Antonio Torres-Castro (ORCID: https://orcid.org/0000-0002-8295-0100)
- J. Restrepo (ORCID: https://orcid.org/0000-0001-6788-040X)
- Fernando P. Monroy (ORCID: https://orcid.org/0000-0002-3466-7466)
- Rodrigo Urrego (ORCID: https://orcid.org/0000-0001-5716-5832)
- Luis Ernesto López (ORCID: https://orcid.org/0000-0003-1736-1307)
- Ronald Guillermo Pelaez Sánchez (ORCID: https://orcid.org/0000-0002-2815-9844)
- Juliana María Martínez Garro (ORCID: https://orcid.org/0000-0001-8984-2340)
- Jorge Emilio Salazar Flórez (ORCID: https://orcid.org/0000-0002-7666-9099)
- Alexandra Milena Cuartas-López (ORCID: https://orcid.org/0000-0003-1885-6707)
- Santiago Pineda
Institutions
- Saint Martin University (CO)
- Northern Arizona University (US)
- Instituto Colombiano de Medicina Tropical (CO)
- Autonomous University of Yucatán (MX)
- Universidad CES (CO)
- Clínica CES (CO)
Publication Details
- Journal
- Pathogens
- Published
- 2025-10-16
- DOI
- https://doi.org/10.3390/pathogens14101044
- Primary Topic
- Leptospirosis research and findings
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Northern Arizona University
- Universidad CES
- Universidad Autónoma de Yucatán