Contemporary Management of Familial and Multifactorial Chylomicronemia Syndromes in Italy: Insights From the National LIPIGEN Registry
As compared with MCS, patients with FCS showed a more severe phenotype and higher prevalence of <i>LPL</i> variants. Lomitapide and volanesorsen provide better triglyceride control, yet only one-third of FCS were treated with these drugs in the routine clinical practice.
Authors
- Matteo Pirro (ORCID: https://orcid.org/0000-0002-5527-4821)
- Giulia Fainelli
- Francesco Baratta (ORCID: https://orcid.org/0000-0003-1708-272X)
- Giuliana Mombelli (ORCID: https://orcid.org/0000-0003-2886-134X)
- S. Calandra (ORCID: https://orcid.org/0000-0001-6386-9174)
- Sabina Zambon
- Matteo Nicola Dario Di Minno (ORCID: https://orcid.org/0000-0001-8059-3819)
- Andrea Bartuli
- Luigi Rizzi (ORCID: https://orcid.org/0000-0003-4877-9861)
- Sergio D’Addato (ORCID: https://orcid.org/0000-0001-6631-4342)
- Federica Galimberti (ORCID: https://orcid.org/0000-0002-4231-4150)
- Manuela Casula (ORCID: https://orcid.org/0000-0002-5124-5361)
- Patrizia Tarugi (ORCID: https://orcid.org/0000-0001-6864-7853)
- Marta Biolo (ORCID: https://orcid.org/0000-0003-2139-0004)
- Salvatore Piro (ORCID: https://orcid.org/0000-0002-1781-0902)
- Gabriella Iannuzzo (ORCID: https://orcid.org/0000-0002-7392-5544)
- Chiara Pavanello (ORCID: https://orcid.org/0000-0001-5892-9857)
- Arianna Toscano (ORCID: https://orcid.org/0000-0001-7817-8042)
- Tiziana Montalcini (ORCID: https://orcid.org/0000-0001-7048-5830)
- Angelo B. Cefalù (ORCID: https://orcid.org/0000-0003-1259-8284)
- Alessia Di Costanzo (ORCID: https://orcid.org/0000-0001-8359-6599)
- Maria Grazia Zenti (ORCID: https://orcid.org/0000-0002-2963-3990)
- Fabio Nascimbeni (ORCID: https://orcid.org/0000-0002-1051-1272)
- Fabio Pellegatta (ORCID: https://orcid.org/0000-0002-9879-1853)
- Maria Donata Di Taranto (ORCID: https://orcid.org/0000-0002-0618-7940)
- Cristina Pederiva (ORCID: https://orcid.org/0000-0002-2213-9383)
- Roberto Scicali (ORCID: https://orcid.org/0000-0002-7023-3649)
- Guglielmo Beccuti (ORCID: https://orcid.org/0000-0003-3163-2361)
- Simone Bini (ORCID: https://orcid.org/0000-0002-1006-4636)
- Paola Sabrina Buonuomo (ORCID: https://orcid.org/0000-0002-7944-8400)
- Simonetta Lugari (ORCID: https://orcid.org/0000-0002-8792-7575)
- Arturo Pujia (ORCID: https://orcid.org/0000-0003-0763-4930)
- Maurizio Averna (ORCID: https://orcid.org/0000-0003-3558-9209)
- Andrea Silvio Benso (ORCID: https://orcid.org/0000-0001-8060-2834)
- Antonina Giammanco (ORCID: https://orcid.org/0000-0002-3088-3049)
- Alberto Zambon (ORCID: https://orcid.org/0000-0001-7096-5201)
- Marcello Arca (ORCID: https://orcid.org/0000-0003-3786-0883)
- Vanessa Bianconi (ORCID: https://orcid.org/0000-0001-6987-9349)
- Daniele Tramontano (ORCID: https://orcid.org/0000-0002-6514-2451)
- Giuseppe Mandraffino (ORCID: https://orcid.org/0000-0003-0272-2237)
- Laura D’Erasmo (ORCID: https://orcid.org/0000-0002-9174-4667)
- Patrizia Suppressa (ORCID: https://orcid.org/0000-0002-3146-9173)
- Ilenia Minicocci (ORCID: https://orcid.org/0000-0002-9801-4501)
- Francesco Sbrana (ORCID: https://orcid.org/0000-0003-4607-0373)
- Alberico L. Catapano (ORCID: https://orcid.org/0000-0002-7593-2094)
- Juliana Lago (ORCID: https://orcid.org/0000-0003-3808-1689)
- Davide Noto
- Liliana Grigore
- Giuseppe Banderali (ORCID: https://orcid.org/0000-0001-6650-981X)
- Beatrice Dal Pino
- Fortunato Giuliana
Institutions
- University of Modena and Reggio Emilia (IT)
- University of Padua (IT)
- University of Milan (IT)
- Policlinico Umberto I (IT)
- MultiMedica (IT)
- Department of Health (ES)
- Instituto di Biofisica (ES)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1161/atvbaha.125.323340
- Citations
- 3
- Primary Topic
- Lipid metabolism and disorders
- Type
- article
- Field-Weighted Citation Impact
- 4.16