In vitro Comparison of Cytotoxicity and Osteoclastogenesis of Four Bioceramic Sealers in Murine Bone Marrow Cells
NeoSEALER Flo, a calcium silicate-based bioceramic sealer, effectively minimises cytotoxicity while inhibiting osteoclast formation and activity. This suggests that it may effectively prevent periapical tissue destruction and promote bone healing in apical periodontitis, highlighting its promising potential as a root canal obturation material.
Authors
- Xiaoyue Sun (ORCID: https://orcid.org/0000-0002-9793-2116)
- Zhuo Chen (ORCID: https://orcid.org/0000-0002-5607-0046)
- Lingxin Zhu (ORCID: https://orcid.org/0000-0002-6762-7882)
- Zijun Wang (ORCID: https://orcid.org/0000-0002-6702-1418)
- Zhijie Chang (ORCID: https://orcid.org/0000-0003-1567-3227)
- Li Ping Wang (ORCID: https://orcid.org/0000-0001-6893-3809)
Institutions
- Wuhan University (CN)
- Stomatology Hospital (CN)
Publication Details
- Journal
- International Dental Journal
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1016/j.identj.2025.103959
- Citations
- 1
- Primary Topic
- Endodontics and Root Canal Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.79