In vitro antitumor effects of PI3K inhibitor linperlisib (YY-20394) on acute myeloid leukemia cells
YY20394 has a favorable inhibitory effect and significant pro-apoptotic effect on the proliferation of AML cells, which suggests that it has some potential for the treatment of AML.
Authors
- Yanli Yang (ORCID: https://orcid.org/0000-0003-1919-8857)
- Jiaqi Chen (ORCID: https://orcid.org/0000-0002-1643-5450)
- Ji Shen (ORCID: https://orcid.org/0000-0002-4324-8538)
- Yan Lou (ORCID: https://orcid.org/0000-0002-2248-0231)
- Yinghua Geng
- Lili Zhou (ORCID: https://orcid.org/0000-0003-4735-5733)
- Wenjuan Wu (ORCID: https://orcid.org/0009-0000-8000-6442)
Institutions
- Bengbu Medical College (CN)
Publication Details
- Journal
- Hematology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1080/16078454.2025.2571812
- Primary Topic
- PI3K/AKT/mTOR signaling in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00