Effects of electroconvulsive shock on astroglial reactivity in a rat model of antipsychotic-induced neurotoxicity
The present study suggests that ES could activate the astrocytic system. Furthermore, our results also showed that ES may mitigate neurotoxic damage induced by antipsychotics. In view of the need for therapeutic strategies for treatment-resistant psychiatric disorders, further investigations of our findings are warranted.
Authors
- Yasunori Oda (ORCID: https://orcid.org/0000-0002-4957-5847)
- Tomihisa Niitsu (ORCID: https://orcid.org/0000-0003-2713-700X)
- Yukihiko Shirayama (ORCID: https://orcid.org/0000-0002-8911-1684)
- Fumiaki Yamasaki
- Fumiaki Yano (ORCID: https://orcid.org/0009-0000-4898-3905)
- Yusuke Nakata (ORCID: https://orcid.org/0009-0003-2816-3733)
- Yuki Hirose (ORCID: https://orcid.org/0009-0004-9570-7072)
Institutions
- Chiba University (JP)
- Chiba University Hospital (JP)
- Teikyo University Chiba Medical Center (JP)
Publication Details
- Journal
- Journal of Psychopharmacology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1177/02698811251382163
- Primary Topic
- Electroconvulsive Therapy Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00