Leptospirosis Prevalence and Risk Factors Among Patients Presenting With Fever to 4 Healthcare Sites in Sub-Saharan Africa and South East Asia: An International Multisite Observational and Nested Case–Control Study
Leptospirosis was a cause of febrile illness at all sites. Some clinical features helped to identify patients with leptospirosis. Interventions related to rice field work and river exposure may prevent disease. Diverse Leptospira serogroup reactivity was observed and may suggest potential hosts.
Authors
- Nicholas Feasey (ORCID: https://orcid.org/0000-0003-4041-1405)
- Yoel Lubell (ORCID: https://orcid.org/0000-0002-0237-1070)
- Risara Jaksuwan (ORCID: https://orcid.org/0000-0002-4258-9058)
- Alessandro Gerada
- Shunmay Yeung (ORCID: https://orcid.org/0000-0002-0997-0850)
- Stuart Dean Blacksell (ORCID: https://orcid.org/0000-0001-6576-726X)
- Kevin C. Kain (ORCID: https://orcid.org/0000-0001-6068-1272)
- Becca L. Handley (ORCID: https://orcid.org/0000-0003-2208-8229)
- Florian P. Maurer (ORCID: https://orcid.org/0000-0001-8353-5964)
- Marie Voice
- Audrey Dubot‐Pérès (ORCID: https://orcid.org/0000-0003-1267-0725)
- Eleanor MacPherson (ORCID: https://orcid.org/0000-0002-7142-1158)
- Vilayouth Phimolsarnnousith (ORCID: https://orcid.org/0000-0001-8180-0007)
- Clare Chandler (ORCID: https://orcid.org/0000-0001-6499-7522)
- John A. Crump (ORCID: https://orcid.org/0000-0002-4529-102X)
- Suzanne Keddie (ORCID: https://orcid.org/0000-0003-1254-7794)
- Mayfong Mayxay (ORCID: https://orcid.org/0000-0002-6056-4516)
- Mabvuto Chimenya
- Catherine M. Davis (ORCID: https://orcid.org/0000-0001-9654-3509)
- Elizabeth Fitchett (ORCID: https://orcid.org/0000-0002-6767-6094)
- Tegwen Marlais (ORCID: https://orcid.org/0000-0003-0955-9807)
- Manivanh Vongsouvath (ORCID: https://orcid.org/0000-0002-2249-7367)
- Amphone Sengduangphachanh
- Heidi Hopkins (ORCID: https://orcid.org/0000-0003-1076-6758)
- Joseph Chipanga (ORCID: https://orcid.org/0000-0002-3938-4983)
- Justin Dixon (ORCID: https://orcid.org/0000-0002-7706-7305)
- Katharina Kranzer (ORCID: https://orcid.org/0000-0001-5691-7270)
- Colin G. Fink (ORCID: https://orcid.org/0000-0002-8008-5870)
- L. Joseph Wheat
- Vilada Chansamouth (ORCID: https://orcid.org/0000-0003-3049-784X)
- Polycarp Mogeni (ORCID: https://orcid.org/0000-0003-1926-7576)
- Ioana D. Olaru (ORCID: https://orcid.org/0000-0003-3392-9257)
- Ampai Tanganuchitcharnchai (ORCID: https://orcid.org/0000-0001-5439-5376)
- Núria Balanza (ORCID: https://orcid.org/0000-0002-3581-0383)
- Molly Sibanda
- Oliver Baerenbold
- Tapan Bhattacharyya (ORCID: https://orcid.org/0000-0003-3385-2536)
- Stephen Graves (ORCID: https://orcid.org/0000-0002-8204-0924)
- Sham Lal (ORCID: https://orcid.org/0000-0002-3650-1398)
- David Mabey (ORCID: https://orcid.org/0000-0002-0031-8276)
- Justina Bramugy (ORCID: https://orcid.org/0000-0002-2350-5584)
- Michael A. Miles (ORCID: https://orcid.org/0000-0002-5834-8734)
- Krishna Singha (ORCID: https://orcid.org/0000-0002-1330-1246)
- Sara Ajanovic (ORCID: https://orcid.org/0000-0002-6137-8619)
- Anélsio Cossa (ORCID: https://orcid.org/0000-0002-3616-8935)
- Christian Bottomley (ORCID: https://orcid.org/0000-0002-5241-8412)
- Xavier Nicolas de Lamballerie (ORCID: https://orcid.org/0000-0001-7895-2720)
- Tsitsi Bandason (ORCID: https://orcid.org/0000-0003-0066-8345)
- David G. Lalloo (ORCID: https://orcid.org/0000-0001-7680-2200)
- John Stenos (ORCID: https://orcid.org/0000-0001-5465-2926)
- Chrissy h. Roberts (ORCID: https://orcid.org/0000-0003-1064-5980)
- Rashida A. Ferrand (ORCID: https://orcid.org/0000-0002-7660-9176)
- Elizabeth A. Ashley (ORCID: https://orcid.org/0000-0002-7620-4822)
- John Bradley (ORCID: https://orcid.org/0000-0002-9449-4608)
- Siho Sengsavang
- Quique Bassat (ORCID: https://orcid.org/0000-0003-0875-7596)
- Manophab Luangraj (ORCID: https://orcid.org/0000-0002-8801-5738)
- Mathieu Picardeau (ORCID: https://orcid.org/0000-0002-5338-5579)
- Ethel Dauya (ORCID: https://orcid.org/0000-0003-3241-2512)
- Jayne Jones
- Campos Mucasse
- Khamfong Kunlaya
- Edward Green (ORCID: https://orcid.org/0000-0002-2440-4355)
- Paul N. Newton (ORCID: https://orcid.org/0000-0003-0734-2022)
- Pankaj Lal (ORCID: https://orcid.org/0000-0002-6555-929X)
- Marta Valente
- James E Ussher
- Chelsea Nguyen (ORCID: https://orcid.org/0000-0003-0674-7423)
- Michelle Durkin
- C. Hutchison
- Brad Amos
- Zumilda Boca
- Jessica Jervis
- Stéphanie Baghoumina
- Somyoth Douangphachanh
- Khamxeng Khounpaseuth
- Sengchanh Manichan
- Hira Tanvir
- Msopole Wamaka
Institutions
- University of Liverpool (GB)
- Institut Pasteur (FR)
- National University of Singapore (SG)
- University of Health Science (KH)
- Liverpool School of Tropical Medicine (GB)
- Mahosot Hospital (LA)
- Malawi-Liverpool-Wellcome Trust Clinical Research Programme (MW)
- Angkor Hospital for Children (KH)
- University of Oxford (GB)
- London School of Hygiene & Tropical Medicine (GB)
- Biomedical Research and Training Institute (ZW)
- University Hospital Münster (DE)
- Ministry of Health of the Russian Federation (RU)
- Manhiça Health Research Centre (MZ)
- Barcelona Institute for Global Health (ES)
- National University Health System (SG)
- University of Health Sciences (SO)
- Universitat de Barcelona (ES)
- University of Otago (NZ)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-08-30
- DOI
- https://doi.org/10.1093/infdis/jiaf464
- Primary Topic
- Leptospirosis research and findings
- Type
- article
- Field-Weighted Citation Impact
- 0.00