The Unseen Threat: Paediatric MRSA Acute Rhinosinusitis Leading to Orbital Complication

Acute rhinosinusitis in children is typically caused by viral or bacterial infections. However, methicillin-resistant Staphylococcus aureus (MRSA) is increasingly linked to recurrence and severe complications, including orbital involvement. We present a case of a 6-year-old boy with periorbital swelling, proptosis, and fever following upper respiratory symptoms. Imaging revealed pansinusitis with a subperiosteal orbital abscess. He was treated empirically with intravenous ceftriaxone and metronidazole, followed by endoscopic sinus surgery. Intraoperative cultures confirmed MRSA, leading to a switch to vancomycin. The patient recovered fully without complications. This case illustrates the clinical challenges posed by MRSA sinusitis and emphasises its public health implications. Integrating antimicrobial stewardship, promoting community hygiene, ensuring early diagnostics and healthcare access, and enhancing epidemiological surveillance can play a pivotal role in reducing the burden of MRSA-related complications in children.

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Publication Details

Journal
Sinusitis
Published
2025-10-16
DOI
https://doi.org/10.3390/sinusitis9020021
Primary Topic
Sinusitis and nasal conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

The Unseen Threat: Paediatric MRSA Acute Rhinosinusitis Leading to Orbital Complication

Farah Dayana Zahedi, Anna Fariza Jumaat, Farid Syamil Ramli
Sinusitis
Sinusitis and nasal conditions
article

The Unseen Threat: Paediatric MRSA Acute Rhinosinusitis Leading to Orbital Complication

Farah Dayana Zahedi, Anna Fariza Jumaat, Farid Syamil Ramli
article en

Abstract

Acute rhinosinusitis in children is typically caused by viral or bacterial infections. However, methicillin-resistant Staphylococcus aureus (MRSA) is increasingly linked to recurrence and severe complications, including orbital involvement. We present a case of a 6-year-old boy with periorbital swelling, proptosis, and fever following upper respiratory symptoms. Imaging revealed pansinusitis with a subperiosteal orbital abscess. He was treated empirically with intravenous ceftriaxone and metronidazole, followed by endoscopic sinus surgery. Intraoperative cultures confirmed MRSA, leading to a switch to vancomycin. The patient recovered fully without complications. This case illustrates the clinical challenges posed by MRSA sinusitis and emphasises its public health implications. Integrating antimicrobial stewardship, promoting community hygiene, ensuring early diagnostics and healthcare access, and enhancing epidemiological surveillance can play a pivotal role in reducing the burden of MRSA-related complications in children.

SinusitisVol. 9(2)
University Kebangsaan Malaysia Medical Centre (MY), National University of Malaysia (MY)
Openalex Percentile: Top 61%
Sinusitis and nasal conditions
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