Design and rationale of the AIR-NET trial: a randomised, open-label, multifactorial, multicentre, adaptive platform trial using a range of repurposed anti-inflammatory treatments to improve outcomes in patients with bronchiectasis within the EMBARC c
AIR-NET will establish a multi-centre network with integrated clinical and translational capabilities for the investigation of therapies in bronchiectasis aiming to identify key anti-inflammatory mechanisms and effective re-purposed treatments.
Authors
- Jeffrey Huang (ORCID: https://orcid.org/0000-0001-9982-2298)
- Michael R. Loebinger
- Jon Stobo (ORCID: https://orcid.org/0000-0003-4829-7440)
- Jaa Ming New (ORCID: https://orcid.org/0000-0002-1692-8204)
- Amy Gilmour
- Charles Haworth (ORCID: https://orcid.org/0000-0001-7126-2874)
- Fiona McLaren-Neil (ORCID: https://orcid.org/0000-0002-9295-3241)
- Holly Lind
- Rebecca C Hull
- Eve Mcintosh
- Aran Singanayagam (ORCID: https://orcid.org/0000-0001-9849-0033)
- Sanjay H. Chotirmall (ORCID: https://orcid.org/0000-0003-0417-7607)
- Anand D. Shah (ORCID: https://orcid.org/0000-0001-5257-520X)
- Thomas S. Wilkinson (ORCID: https://orcid.org/0000-0003-0397-6079)
- Anthony De Soyza (ORCID: https://orcid.org/0000-0002-8566-0344)
- Bridget Harris
- Margaret Band
- Zsofia Eke (ORCID: https://orcid.org/0000-0002-5048-5785)
- James D. Chalmers (ORCID: https://orcid.org/0000-0001-5514-7868)
- R.B. Galloway
- Merete Bridget Long
Institutions
- University of Ulster (GB)
- Nanyang Technological University (SG)
- University of Dundee (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Royal Papworth Hospital (GB)
- NHS Tayside (GB)
- Tan Tock Seng Hospital (SG)
- Royal Brompton Hospital (GB)
- Lung Institute (US)
- NIHR Imperial Biomedical Research Centre (GB)
- Royal Victoria Hospital (GB)
- University of Southampton (GB)
- Imperial College London (GB)
- Newcastle University (GB)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1183/23120541.00719-2025
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00