Effect of short-term supplemental oxygen therapy on six-minute walk distance in highlanders at risk for pulmonary hypertension: a randomized, crossover trial
In hypoxaemic highlanders at risk for HAPH, portable low-dose SOT did not improve 6MWD, despite lower dyspnoea perception, lower heart rates and higher <i>S</i> <sub>pO<sub>2</sub></sub> at end-exercise. This indicates that low-dose SOT oxygen, as commonly applied in various clinical settings, does not increase 6MWD. Whether it reduces cardiovascular stress during exercise needs to be further studied.
Authors
- Talant Sooronbaev (ORCID: https://orcid.org/0000-0002-6511-5963)
- Silvia Ulrich (ORCID: https://orcid.org/0000-0002-5250-5022)
- Alessandro Vella (ORCID: https://orcid.org/0009-0003-9142-7308)
- Julian Müller (ORCID: https://orcid.org/0000-0003-4059-5937)
- Mona Lichtblau (ORCID: https://orcid.org/0000-0003-4485-1758)
- Laura Mayer
- Dinah Hertig (ORCID: https://orcid.org/0000-0001-7809-3065)
- Alina Häfliger (ORCID: https://orcid.org/0009-0006-2182-4203)
- Michaël Furian (ORCID: https://orcid.org/0000-0002-8518-5029)
- Simon Schneider (ORCID: https://orcid.org/0000-0003-3635-0515)
- Anna Titz (ORCID: https://orcid.org/0000-0001-7431-1643)
- Maamed Mademilov (ORCID: https://orcid.org/0000-0001-8528-3115)
- Lena Reimann (ORCID: https://orcid.org/0009-0007-6085-2220)
- Adilet Omuralieva
- Kay von Grünigen
Institutions
- University of Zurich (CH)
- University Hospital of Zurich (CH)
- National Center of Cardiology and Internal Medicine (KG)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1183/23120541.00724-2025
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00