Clinical Presentation, Genetic Testing, and Outcome of Congenital Nephrotic Syndrome in KwaZulu-Natal, South Africa
South African black children are diagnosed with high rates of CNS attributed to untreated maternal CMV and HIV infections likely resulting from limited prenatal maternal care in this population. The diagnostic genetic yield was much less than expected, most likely due to the small number of patients tested compared to larger studies in Western settings, indicating a need for further investigation of the genetic landscape of CNS in African populations.
Authors
- Louansha Nandlal (ORCID: https://orcid.org/0000-0003-0294-2328)
- Cheryl Ann Winkler (ORCID: https://orcid.org/0000-0001-5552-0917)
- Rajendra Bhimma (ORCID: https://orcid.org/0000-0003-3092-7790)
- Thajasvarie Naicker (ORCID: https://orcid.org/0000-0001-6917-2191)
- Victor A. David (ORCID: https://orcid.org/0000-0002-7865-8481)
- Sungkweon Cho
Institutions
- Frederick National Laboratory for Cancer Research (US)
- University of KwaZulu-Natal (ZA)
Publication Details
- Journal
- The Nephron journals/Nephron journals
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1159/000547698
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.00