The Brophy Kit™: An in vivo Experimental Model of Ultrafiltration for Extremely Low Birthweight Neonates
This proof-of-concept study demonstrates the feasibility of using the Brophy Kit™ for manual UF in a preclinical model approximating ELBW neonates. The device shows potential as an accessible solution for fluid management in resource-limited settings.
Authors
- Jolyn Morgan
- Stuart L. Goldstein (ORCID: https://orcid.org/0000-0003-3711-8785)
- Cara Slagle (ORCID: https://orcid.org/0000-0003-4880-9792)
- Apaara K. Chawla
- James E. Rose (ORCID: https://orcid.org/0000-0002-7119-1831)
- Giovanni Ceschia (ORCID: https://orcid.org/0009-0003-1881-9989)
- Rebecca Coriolan
- Michelle C. Starr (ORCID: https://orcid.org/0000-0001-9412-8950)
- Danielle E. Soranno (ORCID: https://orcid.org/0000-0001-7019-809X)
- Carl Russell (ORCID: https://orcid.org/0009-0004-2451-2120)
- Denise C. Hasson
- Amanda Moore
- Angus Stergar
- Edward Plute
Institutions
- Indiana University Health (US)
- Cincinnati Children's Hospital Medical Center (US)
- University of Padua (IT)
- Eli Lilly (United States) (US)
- Purdue University West Lafayette (US)
- Riley Hospital for Children (US)
- NYU Langone Health (US)
- Martinez VA Medical Center (US)
- Indiana University Bloomington (US)
- Washington University Medical Center (US)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
- University of Cincinnati (US)
Publication Details
- Journal
- Blood Purification
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1159/000548882
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00