IGF2BP2 contributes to thyroid cancer progression by enhancing the stability of m6A-modified CTSH mRNA
IGF2 BP2 accelerates TC progression by recognizing and stabilizing m6A-modified CTSH mRNA. IGF2 BP2 and CTSH represent potential diagnostic and therapeutic targets for TC.
Authors
- Xiaofen Qi (ORCID: https://orcid.org/0000-0002-0392-5565)
- Liangpeng Dong (ORCID: https://orcid.org/0009-0009-5731-3239)
- Youwei Li (ORCID: https://orcid.org/0000-0001-7701-5452)
- Lingyun Chen (ORCID: https://orcid.org/0000-0002-1041-5168)
- Min Hou (ORCID: https://orcid.org/0009-0006-8860-9938)
- Qiaochu Lu
Institutions
- First Affiliated Hospital of Xinxiang Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1371/journal.pone.0332061
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00