Trends in Persons Prescribed HIV Postexposure Prophylaxis in the United States, 2015–2023

Our analysis found an increasing trend in PEP use annually, possibly reflecting greater PEP awareness and broader HIV prevention efforts. Increased use of a bictegravir-based PEP regimen in 2023 suggests a shift in PEP prescribing practices, likely due to its once-daily dosing and high tolerability. Our findings can guide future recommendations for PEP medications.

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Publication Details

Journal
Clinical Infectious Diseases
Published
2025-10-16
DOI
https://doi.org/10.1093/cid/ciaf581
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
0.00
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Trends in Persons Prescribed HIV Postexposure Prophylaxis in the United States, 2015–2023

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Trends in Persons Prescribed HIV Postexposure Prophylaxis in the United States, 2015–2023

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article en

Abstract

Our analysis found an increasing trend in PEP use annually, possibly reflecting greater PEP awareness and broader HIV prevention efforts. Increased use of a bictegravir-based PEP regimen in 2023 suggests a shift in PEP prescribing practices, likely due to its once-daily dosing and high tolerability. Our findings can guide future recommendations for PEP medications.

Clinical Infectious DiseasesVol. 82(2)
Centers for Disease Control and Prevention (US), National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention (US)
Openalex Percentile: Top 65%
HIV/AIDS Research and Interventions
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