Tumor-derived exosomal miR-199b-5p promotes proliferation and epithelial-mesenchymal transition in non-small cell lung cancer by targeting CCNL1

Overexpression of miR-199b-5p promotes proliferation, migration, and EMT in lung cancer cells by targeting CCNL1, with its downstream regulatory effects mediated through the Wnt/β-catenin signaling.

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Publication Details

Journal
Translational Oncology
Published
2025-10-16
DOI
https://doi.org/10.1016/j.tranon.2025.102564
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Tumor-derived exosomal miR-199b-5p promotes proliferation and epithelial-mesenchymal transition in non-small cell lung cancer by targeting CCNL1

Bangzhu Liu, Miao Li, Rui Yan, Linian Huang
Translational Oncology
Extracellular vesicles in disease
article

Tumor-derived exosomal miR-199b-5p promotes proliferation and epithelial-mesenchymal transition in non-small cell lung cancer by targeting CCNL1

Bangzhu Liu, Miao Li, Rui Yan, Linian Huang
article en

Abstract

Overexpression of miR-199b-5p promotes proliferation, migration, and EMT in lung cancer cells by targeting CCNL1, with its downstream regulatory effects mediated through the Wnt/β-catenin signaling.

Translational OncologyVol. 62
Wuhu Fourth People Hospital (CN), First Affiliated Hospital of Bengbu Medical College (CN), Anhui Normal University (CN)
Openalex Percentile: Top 74%
Extracellular vesicles in disease
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