Immuno-informatics voyage through molecular mimicry of Heat Shock Proteins: Potential IBD immunopathogenesis
The study provided evidence of molecular mimicry between microbial and human HSPs, which could serve as molecular targets for cross-reactive T cells. In addition to considering sequence similarity, our study emphasized the importance of structural interactions as essential factors in cell signaling and immunological pathways.
Authors
- Saied Hosseini-Asl
- Mahsa Alem (ORCID: https://orcid.org/0000-0002-6787-3311)
- Farhad Pourfarzi (ORCID: https://orcid.org/0000-0001-6442-6340)
- Nasim Hajighahramani (ORCID: https://orcid.org/0000-0003-4400-2692)
- Seyyed Meysam Abtahi Froushani (ORCID: https://orcid.org/0000-0003-2579-6618)
- Rasoul Nemati
Institutions
- Ardabil University of Medical Sciences (IR)
- Urmia University (IR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1371/journal.pone.0333618
- Citations
- 1
- Primary Topic
- Escherichia coli research studies
- Type
- article
- Field-Weighted Citation Impact
- 1.80