Nr4a1 Deficiency Potentially Promotes Hearing Loss Through Inner Ear Immunity in C57BL/6N Mice
Nr4a1 deficiency in C57BL/6N mice exacerbates age-related hearing loss, accompanied by structural changes in synapses and ANFs, potentially resulting from genetic alterations and immune system disruptions.
Authors
- Yanbing Lai (ORCID: https://orcid.org/0000-0002-1031-3364)
- Dan Bing (ORCID: https://orcid.org/0000-0003-4094-0075)
- Hanqi Chu (ORCID: https://orcid.org/0000-0003-0977-622X)
- Bo Su (ORCID: https://orcid.org/0000-0002-4832-1837)
- Maohua Wang (ORCID: https://orcid.org/0000-0002-5985-2430)
- Xiaodi Wang (ORCID: https://orcid.org/0000-0002-5808-2059)
- Fang Yang (ORCID: https://orcid.org/0009-0008-4162-5505)
Institutions
- First People's Hospital of Foshan (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Otology & Neurotology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1097/mao.0000000000004625
- Primary Topic
- Hearing, Cochlea, Tinnitus, Genetics
- Type
- article
- Field-Weighted Citation Impact
- 0.00