Pathogenic Germline Variants in Cancer Susceptibility Genes
This cross-sectional analysis uses data from the All of Us study to estimate the population-level prevalence in US adults of pathogenic variants in key cancer susceptibility genes.
Authors
- Joshua Arbesman (ORCID: https://orcid.org/0000-0002-6601-7580)
- Ying Ni (ORCID: https://orcid.org/0000-0002-0338-5239)
- Gideon Idumah
- Isabella Ribaudo (ORCID: https://orcid.org/0000-0003-1153-7316)
- Daphne Newell
- Madeleine Hadrys
Institutions
- Cleveland Clinic (US)
- Cleveland Clinic Lerner College of Medicine (US)
- University School (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- JAMA
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1001/jama.2025.16372
- Citations
- 4
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 7.27