Exploring the role of routine brain imaging in detecting asymptomatic brain metastases in first diagnosed HER2-positive breast cancer

This study found limited benefit in routine MRI for detecting asymptomatic brain metastases in HER2-positive breast cancer, given the low prevalence (3.6%). A targeted imaging approach for high-risk patients, like those with the absence of Hormon receptors and higher stage tumors, may be effective.

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Publication Details

Journal
PLoS ONE
Published
2025-10-16
DOI
https://doi.org/10.1371/journal.pone.0334610
Primary Topic
Brain Metastases and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploring the role of routine brain imaging in detecting asymptomatic brain metastases in first diagnosed HER2-positive breast cancer

Carmen Leser, Olgica Zaric, Daphne Gschwantler‐Kaulich, Christine Deutschmann et al.
PLoS ONE
Brain Metastases and Treatment
article

Exploring the role of routine brain imaging in detecting asymptomatic brain metastases in first diagnosed HER2-positive breast cancer

Carmen Leser, Olgica Zaric, Daphne Gschwantler‐Kaulich, Christine Deutschmann, Georg Dorffner, Fiona Kabashi
article en

Abstract

This study found limited benefit in routine MRI for detecting asymptomatic brain metastases in HER2-positive breast cancer, given the low prevalence (3.6%). A targeted imaging approach for high-risk patients, like those with the absence of Hormon receptors and higher stage tumors, may be effective.

PLoS ONEVol. 20(10)
Danube Private University (AT), Universität für Weiterbildung Krems (AT), Austrian Research Institute for Artificial Intelligence (AT), Karl Landsteiner Society (AT), Medical University of Vienna (AT)
Openalex Percentile: Top 58%
Brain Metastases and Treatment
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