Lumbar Psammomatous Spinal Meningioma with Osseous Metaplasia: A Rare Location and Diagnostic Challenge

Psammomatous meningiomas are rare, low-grade spinal tumors characterized by the presence of psammoma bodies, which often overlap with metaplastic meningiomas that exhibit osseous components. This overlap presents a diagnostic challenge due to the presence of both shared and distinct pathological features. This case report describes the case of a 76-year-old woman who presented with chronic left buttock pain and progressive difficulty in ambulation. Imaging studies, including lumbar radiography, magnetic resonance imaging, and computed tomography, revealed a well-defined calcified intradural extramedullary mass at the L1 level of the spinal canal. Under general anesthesia with intraoperative neuromonitoring, T12 subtotal laminectomy and L1 total laminectomy were performed, enabling en bloc resection of the tumor. Histopathological analysis confirmed psammomatous meningioma with osseous metaplasia, characterized by psammoma bodies surrounded by meningothelial cells and metaplastic bone formation. This case highlights the importance of differentiating overlapping pathological entities to achieve accurate diagnosis and optimal surgical management.

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Publication Details

Journal
The Nerve
Published
2025-10-14
DOI
https://doi.org/10.21129/nerve.2025.00703
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
Field-Weighted Citation Impact
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article

Lumbar Psammomatous Spinal Meningioma with Osseous Metaplasia: A Rare Location and Diagnostic Challenge

Sung-Bum Kim, Il‐Tae Jang, Jun-Yong Cha, Jae Hyeon Lim et al.
The Nerve
Neurofibromatosis and Schwannoma Cases
article

Lumbar Psammomatous Spinal Meningioma with Osseous Metaplasia: A Rare Location and Diagnostic Challenge

Sung-Bum Kim, Il‐Tae Jang, Jun-Yong Cha, Jae Hyeon Lim, Sang-Soo Choi
article en

Abstract

Psammomatous meningiomas are rare, low-grade spinal tumors characterized by the presence of psammoma bodies, which often overlap with metaplastic meningiomas that exhibit osseous components. This overlap presents a diagnostic challenge due to the presence of both shared and distinct pathological features. This case report describes the case of a 76-year-old woman who presented with chronic left buttock pain and progressive difficulty in ambulation. Imaging studies, including lumbar radiography, magnetic resonance imaging, and computed tomography, revealed a well-defined calcified intradural extramedullary mass at the L1 level of the spinal canal. Under general anesthesia with intraoperative neuromonitoring, T12 subtotal laminectomy and L1 total laminectomy were performed, enabling en bloc resection of the tumor. Histopathological analysis confirmed psammomatous meningioma with osseous metaplasia, characterized by psammoma bodies surrounded by meningothelial cells and metaplastic bone formation. This case highlights the importance of differentiating overlapping pathological entities to achieve accurate diagnosis and optimal surgical management.

The NerveVol. 11(2)
Wooridul Hospital (KR)
Openalex Percentile: Top 58%
Neurofibromatosis and Schwannoma Cases
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