Repeat Intraocular Sampling and Microbiological Testing in Infectious Endophthalmitis: A 27‐Year Prospective Observational Study at an Australian Statewide Tertiary Referral Centre
Our study demonstrated the trends and utility of repeated and different ocular tissue sampling in challenging endophthalmitis. Aqueous taps are most useful at the first biopsy, beyond which it has little diagnostic value. A second sampling can be valuable in patients who are initially culture-negative. Surgical specimens contribute meaningfully to the overall culture yield and enhance cumulative culture positivity.
Authors
- Maedbh Rhatigan
- Pravena Kumaran
- Zelia K. Chiu (ORCID: https://orcid.org/0000-0001-5219-4511)
- Penelope J. Allen (ORCID: https://orcid.org/0000-0001-5916-1253)
- Rosie Dawkins (ORCID: https://orcid.org/0000-0002-7927-8851)
- Jasmine Lichtenstein
Institutions
- The University of Melbourne (AU)
- University Hospital Galway (IE)
- The Royal Victorian Eye & Ear Hospital (AU)
- Centre for Eye Research Australia (AU)
- Melbourne Clinic (AU)
Publication Details
- Journal
- Clinical and Experimental Ophthalmology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1111/ceo.70003
- Citations
- 2
- Primary Topic
- Ocular Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.41
Funders
- University of Melbourne