Multimodal MRI study of gray matter and functional connectivity abnormalities in adolescents with bipolar disorder
Our findings suggest that adolescent BD is characterized by functional abnormalities within DMN and FPN, as well as cerebellar gray matter atrophy. Disrupted structure-function coupling in these regions may reflect possible neurobiological mechanisms underlying BD during adolescence.
Authors
- Pengyu Zhu (ORCID: https://orcid.org/0000-0003-1771-9073)
- Junhuai Xiang (ORCID: https://orcid.org/0000-0002-4419-9651)
- Yuxi Wang (ORCID: https://orcid.org/0000-0002-9754-8181)
- Kun Qin (ORCID: https://orcid.org/0000-0003-1254-6388)
- Lulu Zou
- Wei Chen (ORCID: https://orcid.org/0000-0001-5090-9915)
- Fang Chen (ORCID: https://orcid.org/0000-0002-0934-6134)
- Xiong Chen (ORCID: https://orcid.org/0009-0004-5620-6785)
- Chunqi Ai
- Junchen Gu
Institutions
- Hubei University of Medicine (CN)
- Taihe Hospital (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-10-16
- DOI
- https://doi.org/10.3389/fpsyt.2025.1664729
- Primary Topic
- Bipolar Disorder and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00