Increased aluminum exposure induces widespread changes in silicon, carbon, and nitrogen metabolism in Entomoneis vertebralis
Differential expression transcriptomics has provided insight into diatom metabolism when exposed to aluminum, highlighting potential targets for metabolic engineering. Furthermore, we identified potential silicification-associated genes using tools based on structure and amino acid composition, advancing our understanding of diatom silicification.
Authors
- Sara Calhoun (ORCID: https://orcid.org/0000-0003-2942-1338)
- Igor V. Grigoriev (ORCID: https://orcid.org/0000-0002-3136-8903)
- Michelle O’Malley (ORCID: https://orcid.org/0000-0002-6065-8491)
- Bradley F. Chmelka (ORCID: https://orcid.org/0000-0002-4450-6949)
- Mark A. Brzezinski (ORCID: https://orcid.org/0000-0003-3432-2297)
- Susanna Seppälä (ORCID: https://orcid.org/0000-0002-2983-3669)
- Hugh M. Purdy (ORCID: https://orcid.org/0000-0001-8427-3599)
- Benjamin S. Twining (ORCID: https://orcid.org/0000-0002-1365-9192)
- R. Ragunathan (ORCID: https://orcid.org/0000-0003-4416-6232)
- Hosu Gwak
Institutions
- Lawrence Berkeley National Laboratory (US)
- University of California, Santa Barbara (US)
- Joint Genome Institute (US)
- Bigelow Laboratory for Ocean Sciences (US)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1186/s12864-025-12106-7
- Primary Topic
- Diatoms and Algae Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00