Navigating The CeRNA Axis by Bioinformatics and Experimental Validation: Identification of <i>ADIRF-AS1</i>, miR-191-5p, and EGR1 as Key Players in Endometrial Carcinoma Progression.

Here, we observed an interaction between lncRNA ADIRF-AS1and hsa-miR-191-5p, and also, ADIRFAS1 downstream effects on EGR1 in EC, that seems may be a suggesting therapeutic and diagnostic targets. Further research could explore its clinical relevance in endometrial carcinoma.

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Publication Details

Journal
PubMed
Published
2025-09-30
DOI
https://doi.org/10.22074/ijfs.2024.2034827.1725
Primary Topic
MicroRNA in disease regulation
Type
article
Field-Weighted Citation Impact
0.00

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article

Navigating The CeRNA Axis by Bioinformatics and Experimental Validation: Identification of ADIRF-AS1, miR-191-5p, and EGR1 as Key Players in Endometrial Carcinoma Progression.

Rahim Rostami, Saman Morovat, Azadeh Rezaei, Soudabeh Fallah et al.
PubMed
MicroRNA in disease regulation
article

Navigating The CeRNA Axis by Bioinformatics and Experimental Validation: Identification of ADIRF-AS1, miR-191-5p, and EGR1 as Key Players in Endometrial Carcinoma Progression.

Rahim Rostami, Saman Morovat, Azadeh Rezaei, Soudabeh Fallah, Shahram Teimourian, Afsaneh Tehranian, Elmira Mehdinia
article en

Abstract

Here, we observed an interaction between lncRNA ADIRF-AS1and hsa-miR-191-5p, and also, ADIRFAS1 downstream effects on EGR1 in EC, that seems may be a suggesting therapeutic and diagnostic targets. Further research could explore its clinical relevance in endometrial carcinoma.

PubMedVol. 19(4)
Iran University of Medical Sciences (IR), Tehran University of Medical Sciences (IR)
Iran University of Medical Sciences
Openalex Percentile: Top 64%
MicroRNA in disease regulation
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