Prospective validation of a pretreatment 18F-FDG PET/CT and mean lung dose model for early radiation pneumonitis
The previously developed SUV<sub>P90</sub> and MLD-based risk model for RP<sub>Early</sub> demonstrated a high probability to correctly predict RP<sub>Early</sub> in the independent cohort. This now validated RP<sub>Early</sub> risk model with derived high-risk indications could enable personalized thoracic RT planning to reduce the risk of RP<sub>Early</sub> and of discontinuing life-prolonging IO post-cCRT.
Authors
- Daphna Y. Gelblum (ORCID: https://orcid.org/0000-0001-7211-6246)
- Mark Dunphy (ORCID: https://orcid.org/0000-0002-1886-1832)
- Narek Shaverdian (ORCID: https://orcid.org/0000-0002-0294-8749)
- Milan Grkovski (ORCID: https://orcid.org/0000-0001-7228-9497)
- Abraham J. Wu (ORCID: https://orcid.org/0000-0002-2597-7091)
- D. Billing
- Puneeth Iyengar (ORCID: https://orcid.org/0000-0003-3740-7915)
- Joseph O. Deasy (ORCID: https://orcid.org/0000-0002-9437-266X)
- Jacob Y. Shin (ORCID: https://orcid.org/0000-0003-1558-3731)
- Maria Thor
- Jennifer Ma (ORCID: https://orcid.org/0000-0001-8133-2282)
- Tafadzwa L. Chaunzwa (ORCID: https://orcid.org/0000-0001-7216-159X)
- Daniel Richard Gomez (ORCID: https://orcid.org/0009-0003-8617-3868)
- Charles B. Simone (ORCID: https://orcid.org/0000-0002-0867-3694)
- Masoud Zarepisheh (ORCID: https://orcid.org/0000-0001-6616-5949)
- Aditya Apte (ORCID: https://orcid.org/0000-0001-8120-0669)
- Jamie E. Chaft (ORCID: https://orcid.org/0000-0002-5838-9982)
Institutions
- Memorial Sloan Kettering Cancer Center (US)
Publication Details
- Journal
- Physics and Imaging in Radiation Oncology
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1016/j.phro.2025.100844
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.00