Effectiveness of Pentavalent Rotavirus Vaccine - a Propensity Score Matched Test Negative Design Case-Control Study Using Medical Big Data in Three Provinces of China.
Three-dose RV5 VE against rotavirus gastroenteritis (RVGE) in children aged < 5 years was higher than 1-2-dose VE. Three-dose VE decreased with time since the 3rd dose in children who received the 3rd dose before turning five months of age, but remained above 60% for at least one year. VE was higher for RVGE hospitalizations than for medically attended outpatient visits.
Authors
- Fan Zhang (ORCID: https://orcid.org/0000-0003-0976-2477)
- Fu Zhen Wang
- Yue Xin Xiu
- Xue Yan Li
- Jing Wu (ORCID: https://orcid.org/0000-0003-2013-2863)
- Zhen Li (ORCID: https://orcid.org/0000-0001-8037-4245)
- Dan Li (ORCID: https://orcid.org/0000-0002-4542-4953)
- Yu Lei (ORCID: https://orcid.org/0000-0003-4321-0385)
- Lin Tang
- Lei Wang (ORCID: https://orcid.org/0000-0003-1454-9283)
- Yi Yao (ORCID: https://orcid.org/0000-0003-4374-2955)
- Zun Dong Yin
- Jun Liu (ORCID: https://orcid.org/0009-0007-0470-221X)
Institutions
- Chinese Center For Disease Control and Prevention (CN)
- Hubei Provincial Center for Disease Control and Prevention (CN)
- Capital Institute of Pediatrics (CN)
- National Institute for Communicable Disease Control and Prevention (CN)
- Guangdong Provincial Center for Disease Control and Prevention (CN)
- Children's Hospital of Capital Institute of Pediatrics (CN)
- Beijing Chaoyang Emergency Medical Center (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-09-20
- DOI
- https://doi.org/10.3967/bes2025.056
- Primary Topic
- Viral gastroenteritis research and epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00